Dental Pulp Stem Cells in Parkinson’s Disease Treatment
This paper studies potential roles for DPSCs in the treatment of Parkinson’s disease.
Methods Mol Biol. 2019 Sep 7. doi: 10.1007/7651_2019_261. [Epub ahead of print]
Gnanasegaran N1,2, Thimiri Govinda Raj DB3, Arumugam S4.
- Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore. [email protected].
- Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia. [email protected].
- Envirotransgene Biosolutions Global, Chennai, India.
- School of Bio Sciences and Technology (SBST), VIT University, Vellore, Tamil Nadu, India.
Several research groups have utilized dental pulp stem cells for numerous studies as treatment modality for Parkinson’s disease (PD). However, the roles of dental pulp stem cells in governing the Parkinson’s disease inflammatory microenvironment remain to be evaluated. In this article, we elaborate the method where we can investigate the effects of dental pulp stem cells on neurons and microglia in an in vitro inflammatory microenvironment.